Influence of an immunological precipitate on D.C. and A.C. behaviour of an isfet

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Influence of an Immunological Precipitate A.c. Behaviour of an Isfet

We propose to detect the charge redistribution of an antibody-antigen complex (a precipitate), formed in a layer on top of an ISFET, by means of a.c. measurements. In fact an increased specific conductivity of the precipitate is detected, caused by the amount of counterions, which is related to the fixed protein charge in the precipitate. We observed that an HSA-antiHSA immune complex, deposite...

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ژورنال

عنوان ژورنال: Sensors and Actuators

سال: 1989

ISSN: 0250-6874

DOI: 10.1016/0250-6874(89)87012-x